. Author manuscript; available in PMC: 2014 Mar 20.

Published in final edited form as: Bioconjug Chem. 2013 Mar 1;24(3):464–472. doi: 10.1021/bc300608h

Table 1.

Physicochemical Characterization of free drug and PTX-loaded PEG_5K-FTS₂ Micelles

Micelle	Molar ratio	Conc. of PTX^a (mg/mL)	Size^b (nm)	PDI^c	DLE^d (%)	DLC^e (%)
PEG_5K-FTS₂	-	-	17.61± 0.9	0.201	-	-
PEG_5K-FTS₂ :PTX	3.75 :1	1	24.93± 1.2	0.354	90.6	3.73
PEG_5K-FTS₂ :PTX	5 :1	1	25.63± 3.4	0.234	97.6	2.82
PEG_5K-FTS₂ :PTX	7.5 :1	1	22.27± 0.6	0.268	98.0	1.90
PEG_5K-FTS₂ :PTX	10 :1	1	20.17± 0.2	0.189	96.2	1.43

PTX concentration in micelle was kept at 1 mg/mL. Blank micelle concentration was 20 mg/mL. Values repotted are the mean ± SD for triplicate samples.

Measured by dynamic light scattering particle sizer.

PDI = polydispersity index.

DLE = drug loading efficiency.

DLC = drug loading capacity.