Effects of sleep deprivation on food intake and body weight in rats. a Average food intake during 6h spontaneous sleep–wake (control, white bar) and during 6 h of sleep deprivation (6h SD, black bar). Food intake was significantly (p=0.008, n=10) higher during the sleep deprivation period when compared to control rats. b Changes in body weight during 6 h of sleep deprivation, food deprivation, and respective controls. During spontaneous sleep–wake, rats showed a decrease in body weight (–7.89±1.06 g). Sleep-deprived rats showed significant higher decreases in body weight when compared to controls. 6h of food deprivation also significantly reduced body weight, but to a lesser extend than 6h SD. When the rats were food- and sleep-deprived at the same time, body weight decreased significantly more, when compared to food deprivation alone. c Correlation between food intake and body weight during 6h SD and respective controls. The rats showed a strong and significant correlation between the amount of food intake and body weight (6h SD (r=0.902, p<0.05), Control (r=0.883, p<0.05))