. Author manuscript; available in PMC: 2013 Apr 12.

Published in final edited form as: Arch Neurol. 2012 Feb;69(2):215–222. doi: 10.1001/archneurol.2011.559

Table 2.

Significant Correlations Between Baseline Regional [¹⁸F]FDDNP Binding Values and Cognitive Domain Change Scores

Cognitive Domain and Region of Interest^a	t₄₁	r^b	P Value^b
Executive functioning
Global	−2.51	−0.36	.02
Frontal	−1.88	−0.29	.06
Parietal	−2.03	−0.30	.05
Medial temporal	−2.65	−0.38	.01
Language
Global	−2.70	−0.39	.01
Parietal	−3.01	−0.42	.004
Medial temporal	−2.07	−0.31	.05
Visuospatial
Global	−1.99	−0.34	.03
Frontal	−2.99	−0.45	.002
Parietal	−2.41	−0.39	.01
Attention and information processing
Global	−2.52	−0.37	.01
Lateral temporal	−2.56	−0.37	.01

Abbreviation: [¹⁸F]FDDNP, 2-(1-{6-[(2-fluorine 18–labeled fluoroethyl)methylamino]-2-napthyl}ethylidene) malononitrile.

Memory domain change scores were not significantly associated with baseline global [¹⁸F]FDDNP binding and hence were not reported in this table.

Spearman correlation coefficient and the associated 2-sided P value.