Fig. 5.
ImmTAC efficacy study in mice co-xenografted with human PBL and J82-NY-ESOGFP157–165 cells. a GFP gated fluorescence time course of representative mice xenografted with human PBL and J82-NY-ESOGFP157–165 cells and treated with ImmTAC-GAG (n = 4), ImmTAC-NYE (n = 4), or PBS (n = 4). b Average fold change in GFP-gated fluorescence for all animals over the time course. Asterisks indicate unpaired Student’s t test statistical analysis of the difference in GFP-gated fluorescence of ImmTAC-NYE- and ImmTAC-GAG-treated mice. Error bars present SEM. *p < 0.05, **p < 0.01, ***p < 0.001