Table 2. Experiment 2.
3-PBC Dose | |||||||||
---|---|---|---|---|---|---|---|---|---|
Alcohol Group | BL | V | 1.0 | 3.0 | 10.0 | 18.0 | F(5,15) | ||
C2-L1 | Left Lev FI Resp | Mean | 144.7 | 169.4 | 106.9 | 115.5 | 36.8 | 116.3 | 0.48 |
SEM | 84.8 | 102.8 | 60.1 | 84.0 | 23.7 | 50.3 | |||
Left Lev FI Resp Latency (s) | Mean | 630.2 | 606.2 | 695.8 | 712.3 | 697.8 | 739.0 | 1.60 | |
SEM | 13.7 | 2.1 | 53.4 | 35.0 | 32.3 | 57.6 | |||
C2-L2 | Left Lev FR Resp Rate (r/s) | Mean | 3.1 | 3.2 | 2.7 | 2.2 | 2.1 | 2.1 | 1.40 |
SEM | 0.3 | 0.5 | 0.5 | 0.3 | 0.7 | 0.7 | |||
C3 | Volume (ml) | Mean | 625.6 | 674.8 | 576.7 | 489.6 | 355.4 | 283.3 | 4.86 |
SEM | 31.2 | 85.1 | 115.0 | 110.6 | 76.5 | 71.2 | |||
g.kg Alc consumed | Mean | 1.13 | 1.12 | 1.00 | 0.90 | 0.67 | 0.48 | 3.85 | |
SEM | 0.1 | 0.1 | 0.2 | 0.1 | 0.2 | 0.1 | |||
Control Group | |||||||||
C2-L1 | Left Lev FI Resp | Mean | 93.4 | 234.5 | 306.7 | 115.4 | 74.2 | 101.3 | 5.30 |
SEM | 21.5 | 73.8 | 129.1 | 44.3 | 49.4 | 72.6 | |||
Left Lev FI Resp Latency (s) | Mean | 606.8 | 610.7 | 616.4 | 710.1 | 711.0 | 676.9 | 0.96 | |
SEM | 0.9 | 2.52 | 12.4 | 56.2 | 87.8 | 70.1 | |||
C2-L2 | Left Lev FR Resp Rate (r/s) | Mean | 3.1 | 2.9 | 2.5 | 2.1 | 1.5 | 1.7 | 3.78 |
SEM | 0.3 | 0.4 | 0.2 | 0.2 | 0.3 | 0.4 | |||
C3 | Volume (ml) | Mean | 1000 | 1000 | 979.2 | 825.0 | 772.9 | 775.0 | 1.84 |
SEM | 0.0 | 0.0 | 20.8 | 175.0 | 88.2 | 125.2 |
Data shown are group means (and SEM) for baseline (BL) and each 3-PBC dose (mg/kg). FI, Fixed Interval; FR, Fixed Ratio; Lev, Lever; Resp, Response; Alc, Alcohol
1An underlined F ratio indicates a significant (p<0.05 ANOVA); bolded numbers indicate a significant p<0.05) Bonferroni's post-hoc test compared to vehicle.