Fig. 2. Mice in the Ascending dosing schedule display a higher magnitude of cocaine conditioned place preference (cocaine CPP) compared to the FL or FH groups.
All 3 groups showed a significant (*p < 0.05 when difference is within group) increase in time (seconds) spent on the cocaine-paired side on the post-test compared to pre-test. The Ascending (Asc) group showed a significantly higher magnitude of cocaine CPP (#p < 0.05 when difference is between groups) compared to the fixed low (FL) and fixed high (FH) groups. Data are represented as mean ± SEM, *p > 0.05, n = 15-16 mice per group.