Table 1.
Demographics, laboratory and substance consumption variables for ALC, PSU and LD (mean ± standard deviation). NS: not significant (p>0.05). FTND: Fagerstrom Tolerance Test for Nicotine Dependence, BMI: body mass index, ALT: alanine aminotransferase, AST: aspartate aminotransferase, GGT: γ-glutamyltransferase, WBC: white blood cell counts, RBC: red blood cell counts.
| Variable | LD | ALC | PSU | p (LD-ALC) |
p (LD-PSU) |
p (ALC-PSU) |
|---|---|---|---|---|---|---|
| n (male, female) | 16 (15, 1) | 40 (37, 3) | 28 (26,2) | - | - | - |
| Age [years] | 49.0 ± 10.1 | 52.1 ± 9.1 | 45.3 ± 9.6 | NS | NS | 0.004 |
| Education [years] | 15.4 ± 2.7 | 13.6 ± 1.8 | 12.8 ± 1.4 | 0.001 | 0.000 | NS |
| Smoker n | 6 | 26 | 18 | - | - | - |
| NART | 116.4 ± 8.0 | 114.8 ± 8.3 | 106.4 ± 9.2 | NS | 0.001 | 0.000 |
|
onset heavy drinking
[age] |
- | 25.0 ± 9.1 | 20.7 ± 7.8 | - | - | NS |
| Months heavy drinking | - | 269 ± 119 | 238 ± 132 | - | - | NS |
| Sober days (alcohol) | - | 32.7 ± 7.5 | 28.6 ± 11.8 | - | - | NS |
| Sober days (any drug) | - | 32.7 ± 7.5 | 27.0 ± 11.9 | - | - | 0.021 |
|
1 year avg. (alcohol)
[Drinks/month] |
22 ± 24 | 377 ± 258 | 302 ± 326 | 0.000 | 0.001 | NS |
|
3 year avg. (alcohol)
[Drinks/month] |
22 ± 24 | 340 ± 206 | 300 ± 318 | 0.000 | 0.000 | NS |
|
Life time avg. (alcohol)
[Drinks/month] |
23 ± 17 | 211 ± 109 | 261 ± 261 | 0.000 | 0.000 | NS |
|
1 year avg. (cocaine)
[g/month] |
- | - | 82.2± 106.2 | - | - | - |
|
Life time avg. (cocaine)
[g/month] |
- | - | 75.2 ± 96.2 | - | - | - |
|
1 year avg.
(methamphetamine) [g/month] |
- | - | 21.2 ± 29.1 | - | - | - |
|
Life time avg.
(methamphetamine) [g/month] |
- | - | 14.1 ± 13.6 | - | - | - |
| FTND total (smokers) | 5.7 ± 2.4 | 4.7 ± 1.7 | 4.0 ± 1.6 | NS | 0.049 | NS |
| cigarettes/day | 21.2 ± 9.7 | 16.8 ± 7.9 | 10.0 ± 7.3 | NS | 0.004 | 0.005 |
| BMI | 25.5± 1.1 | 26.3± 0.7 | 27.9± 0.9 | NS | 0.085 | NS |
| Prealbumin [mg/dl] | 29.2 ± 5.8 | 25.8 ± 5.7 | 30.2 ± 7.0 | NS | NS | 0.009 |
| GGT [U/l] | 42.9 ± 78.5 | 72.1 ± 117.4 | 39.9 ± 71.1 | NS | NS | NS |
| Albumin [mg/dl] | 4.2 ± 0.3 | 4.1 ± 0.3 | 4.2 ± 0.2 | NS | NS | NS |
| AST [U/l] | 49.2 ± 82.1 | 41.2 ± 52.4 | 39.9 ± 60.9 | NS | NS | NS |
| ALT [U/l] | 51.0 ± 93.2 | 44.2 ± 67.6 | 41.0 ± 51.1 | NS | NS | NS |
| WBC [K/cmm] | 6.1 ± 1.6 | 7.2 ± 2.1 | 6.2 ± 1.7 | 0.10 | NS | 0.039 |
| RBC [M/cmm] | 4.7 ± 0.4 | 4.5 ± 0.5 | 4.6 ± 0.4 | NS | NS | NS |
| Hemoglobin [g/dl] | 15.0 ± 1.0 | 14.4 ± 1.3 | 14.4 ± 1.0 | NS | NS | NS |
| Hematocrit [%] | 43.3 ± 3.3 | 42.0 ± 3.9 | 42.6 ± 3.1 | NS | NS | NS |
| MCV [fl] | 92.0 ± 4.1 | 93.7 ± 4.5 | 91.8 ± 4.9 | NS | NS | NS |
| BDI | 5.8 ± 2.2 | 12.2 ± 1.4 | 11.7 ± 1.5 | 0.017 | 0.031 | NS |
| State t anxiety y2 | 35.0 ± 3.0 | 44.3 ± 1.8 | 43.0 ± 2.0 | 0.010 | 0.030 | NS |
| State t anxiety y1 | 26.3 ± 2.8 | 33.9 ± 1.6 | 34.2 ± 1.8 | 0.020 | 0.019 | NS |