Table 5.

Characteristics of MALDI Mass Spectrometers used for IMS.

Mass Analyzer	Mass Resolving Power (m/Δm)	m/z Range	Throughput (pixels/sec)	Tandem MS Capabilities	Application
Linear TOF	103	0 – 106	2 – 5	No	Peptides/ Proteins
Reflectron TOF	103 – 104	0 – 105	2 – 5	MS2 (post-source decay)	Drug/Metabolites/Peptides/Lipids
TOF/TOF	103 – 104	0 – 104	2 – 5	MS2
Q-TOF	103 – 104	100 – 6k	< 1	MS2
Linear Ion Trap	102 – 103	50 – 3k	< 1	MSn
Triple Quadrupole	102 – 103	50 – 5k	> 100	MS2
FT-Orbitrap	104 – 105	50 – 10k	< 1	MSn
FT-ICR	104 – 106	100 – 10k	1 – 3	MSn