TABLE 2.
Clinical Features of Superficial Spreading and Nodular Melanoma
| Clinical Features | Superficial Spreading, n=812, No. (%) | Nodular, n=126, No. (%) | P |
|---|---|---|---|
| Border regularity | |||
| Regular | 243 (29.9) | 48 (38.1) | .004 |
| Moderately irregular | 435 (53.6) | 70 (55.6) | |
| Very irregular | 94 (11.6) | 3 (2.4) | |
| Unknown | 40 (4.9) | 5 (4.0) | |
| First dominant color | |||
| Black | 254 (31.3) | 54 (42.9) | <.0001 |
| Brown | 384 (47.3) | 33 (26.2) | |
| Red | 55 (6.8) | 17 (13.5) | |
| Other | 107 (13.2) | 20 (15.9) | |
| Unknown | 12 (1.5) | 2 (1.6) | |
| Second dominant color | |||
| Black | 113 (13.9) | 6 (4.8) | .003 |
| Brown | 131 (16.1) | 25 (19.8) | |
| Light brown | 143 (17.6) | 11 (8.7) | |
| Red | 49 (6.0) | 9 (7.1) | |
| Other | 84 (10.3) | 19 (15.1) | |
| None | 292 (36.0) | 56 (44.4) | |
| Unknown | 0 (0) | 0 (0) | |
| Color pattern | |||
| Uniform | 248 (30.5) | 54 (42.9) | .006 |
| Variegated | 544 (67.0) | 69 (54.8) | |
| Unknown | 20 (2.5) | 3 (2.4) | |
| Change in lesion | |||
| Yes | 680 (83.7) | 116 (92.1) | .06 |
| No | 102 (12.6) | 9 (7.1) | |
| Unknown | 30 (3.7) | 1 (0.80) | |
| Change in size | |||
| Decrease | 9 (1.1) | 4 (3.2) | .21 |
| Increase | 439 (54.1) | 69 (54.8) | |
| No change | 305 (37.6) | 49 (38.9) | |
| Unknown | 59 (7.3) | 4 (3.2) | |
| Change in elevation | |||
| Increase | 400 (49.3) | 95 (75.4) | <.0001 |
| Decrease | 16 (2.0) | 1 (0.80) | |
| No change | 357 (44.0) | 28 (22.2) | |
| Unknown | 39 (4.8) | 2 (1.6) | |
| Change in color | |||
| Yes | 419 (51.6) | 81 (64.3) | .01 |
| No | 333 (41.0) | 38 (30.2) | |
| Unknown | 60 (7.4) | 7 (5.6) | |
| Duration of melanoma, mean, median (mo) | 27.9, 9.0 | 25.3, 5.0 | .004 |
| Largest diameter, mean, median (mm) | 18.3, 15.0 | 14.8, 12.0 | .01 |
| Elevation, mean, median (mm) | 2.2, 1.0 | 4.2, 3.5 | <.0001 |