Table 2.
35-Gene signature of vascular invasion.
| Gene ID | Gene symbol | Gene name | Over-expressed in | Signal-to-noise ratio |
|---|---|---|---|---|
| 100133941 | CD24 | CD24 molecule | VI | 0.50 |
| 25796 | PGLS | 6-phosphogluconolactonase | VI | 0.41 |
| 3069 | HDLBP | high density lipoprotein binding protein (vigilin) | VI | 0.40 |
| 26003 | GORASP2 | golgi reassembly stacking protein 2, 55 kDa | VI | 0.38 |
| 7298 | TYMS | thymidylate synthetase | VI | 0.37 |
| 11065 | UBE2C | ubiquitin-conjugating enzyme E2C | VI | 0.37 |
| 1362 | CPD | carboxypeptidase D | VI | 0.37 |
| 11260 | XPOT | exportin, tRNA (nuclear export receptor for tRNAs) | VI | 0.36 |
| 55249 | YY1AP1 | YY1 associated protein 1 | VI | 0.36 |
| 1033 | CDKN3 | cyclin-dependent kinase inhibitor 3 (CDK2-associated dual specificity phosphatase) | VI | 0.34 |
| 26502 | NARF | nuclear prelamin A recognition factor | VI | 0.33 |
| 10945 | KDELR1 | KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 1 | VI | 0.33 |
| 283820 | NOMO2 | NODAL modulator 2 | VI | 0.33 |
| 4728 | NDUFS8 | NADH dehydrogenase (ubiquinone) Fe-S protein 8, 23 kDa (NADH-coenzyme Q reductase) | VI | 0.25 |
| 5053 | PAH | phenylalanine hydroxylase | no VI | −0.32 |
| 10891 | PPARGC1A | peroxisome proliferative activated receptor, gamma, coactivator 1, alpha | no VI | −0.32 |
| 10747 | MASP2 | mannan-binding lectin serine peptidase 2 | no VI | −0.33 |
| 91614 | DEPDC7 | DEP domain containing 7 | no VI | −0.34 |
| 10249 | GLYAT | glycine-N-acyltransferase | no VI | −0.34 |
| 7366 | UGT2B15 | UDP glucuronosyltransferase 2 family, polypeptide B15 | no VI | −0.34 |
| 7763 | ZFAND5 (ZA20D2) | zinc finger, AN1-type domain 5 | no VI | −0.35 |
| 687 | KLF9 | Kruppel-like factor 9 | no VI | −0.35 |
| 1576 | CYP3A4 | cytochrome P450, family 3, subfamily A, polypeptide 4 | no VI | −0.36 |
| 55089 | SLC38A4 | solute carrier family 38, member 4 | no VI | −0.36 |
| 5295 | PIK3R1 | phosphoinositide-3-kinase, regulatory subunit 1 (p85 alpha) | no VI | −0.36 |
| 5444 | PON1 | paraoxonase 1 | no VI | −0.38 |
| 1807 | DPYS | dihydropyrimidinase | no VI | −0.39 |
| 54407 | SLC38A2 | solute carrier family 38, member 2 | no VI | −0.40 |
| 92292 | GLYATL1 | glycine-N-acyltransferase-like 1 | no VI | −0.40 |
| 5105 | PCK1 | phosphoenolpyruvate carboxykinase 1 (soluble) | no VI | −0.40 |
| 4638 | MYLK | myosin, light chain kinase | no VI | −0.40 |
| 10157 | AASS | aminoadipate-semialdehyde synthase | no VI | −0.41 |
| 4143 | MAT1A | methionine adenosyltransferase I, alpha | no VI | −0.44 |
| 127 | ADH4 | alcohol dehydrogenase 4 (class II), pi polypeptide | no VI | −0.46 |
| 10171 | RCL1 | RNA terminal phosphate cyclase-like 1 | no VI | −0.48 |
VI, vascular invasion.
Gene ID indicates National Center for Biotechnology Information's Entrez GeneID.