Effects of pargyline on histone marks. a MDA-MB-231 and MDA-MB-468 cells were treated with increasing concentrations of pargyline for 48 h. MTT assays were performed. * P < 0.05, *** P < 0.001, (pargyline vs. control, Student’s t-test). b MDA-MB-231 cells were treated with indicated concentrations of pargyline for 24 h and analyzed by immunoblots for expression of H3K4me2, H3k4me1, and AcH3. c MDA-MB-231 cells were exposed to 5 µM pargyline or 5 mM SAHA for 24 h and analyzed for expression of indicated proteins by immunoblots. H3 was used as a loading control