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. 2013 May;33(9):1711–1722. doi: 10.1128/MCB.01151-12

Fig 2.

Fig 2

Glucocorticoids induce repression of the GR gene by inhibiting transcription in mice and rats. (A and B) Primary GR transcript levels were measured in HTC cells and 3T3L cells, using primers and probes specific for nascent GR transcripts in rats and mice, respectively. (C, D, E, and F) Adrenalectomized mice were treated with dexamethasone or PBS for different intervals, and then the mice were euthanized, followed by extraction of the liver, kidney, lung, and heart for RNA isolation. Quantitative RT-PCR was then performed to determine the levels of mGR primary transcript. The data represent the means ± SD for three independent experiments. **, P < 0.01; *, P < 0.05.