Fig 6.
Acot7N−/− mice show maladaptive response to stimulus-evoked behavior. (A and B) Movement of 3- to 4-month-old control and Acot7N−/− female mice, monitored by CLAMS, graphed over time (A) or in 6-h binned increments (B); n = 5 to 7. (C and D) Energy expenditure of control and Acot7N−/− female mice, monitored by CLAMS and graphed over time (C) or in 6-h binned increments (D); n = 5 to 7. (E) Change in body temperature of 5- to 6-month-old male and female control and Acot7N−/− mice during a 6-h cold exposure with or without overnight fasting. (F) Prepulse inhibition from acoustic startle response in 3- to 5-month-old male and female control and Acot7N−/− mice; n = 17 to 20. Data represent averages ± standard errors of the means. “∗” indicates P ≤ 0.05 by a two-tailed Student t test comparing controls to Acot7N−/− mice.