Fig 4.

PTP61FΔ mutant flies have a decreased life span. The life span of PTP61FΔ (arm-Gal4/+; PTP61FΔ) female flies is significantly reduced compared to that of w¹¹¹⁸ female controls (P < 0.0001). Constitutive overexpression of PTP61Fm and PTP61Fn in the PTP61FΔ background using arm-Gal4 (arm>PTP61Fm+n; PTP61FΔ) is sufficient to rescue the life span defect of PTP61FΔ mutants; however, overexpression of PTP61Fn alone using arm-Gal4 (arm>PTP61Fn; PTP61FΔ) does not rescue the life span defect. n = 30 to 50. Statistical analysis was performed using the log rank test.