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. 2013 May;87(9):4835–4845. doi: 10.1128/JVI.01085-12

Fig 1.

Fig 1

Downregulation of human NK cell-mediated cytotoxicity pathway genes in response to Gal-9. Among the genes downregulated in response to Gal-9 stimulation are genes of the NK cell-mediated cytotoxicity pathway, including the natural cytotoxicity triggering receptors 1 (NCR1/NKp46) and 3 (NCR3/NKp30) as well as CD48, CD16 (FCGR3A), the killer cell immunoglobulin-like receptor KIR3DL2, the lymphocyte cytosolic protein LCP2/SLP-76, the perforin 1 pore-forming gene PRF1, and the v-Ha-ras Harvey rat sarcoma viral oncogene homolog HRAS/Ras. This pathway was derived from the KEGG pathway database (50).