Fig 3.

IFN-α production not dependent on TLRs. The impact of TLR adaptor molecules MyD88 (A and B) and TRIF (C and D) or of TLR3 (E and F) on type I IFN production was determined in cDCs and macrophages. The IFN-α levels were determined via ELISA from a cell sample harvested at 24 h. The data represent mean values ± the standard deviations based on triplicate wells from a representative experiment. Each experiment was performed at least three times. NS (not significant), P > 0.05. BLD, below the limit of detection.