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Survival following RVFV infection is dependent on the route of infection and MAVS. (A) Mice were infected either subcutaneously or intranasally and were monitored daily for death or severe morbidity (five mice per group). (B) WT (n = 12) or Mavs−/− (n = 13) mice were challenged intranasally and monitored daily for 28 days. All infections were performed with 3.5 × 104 PFU of rMP-12. Significance: **, P ≤ 0.01.
