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Differences of van der Waals interaction potentials between the mutant and WT protease inhibitor complexes. (A) APV complex; (B) DRV complex; (C) ATV complex. The vdW interaction values are averaged per residue for the inhibitor complexes when there are two dimers in the asymmetric unit. Protease variants are colored blue for I50V/A71V and red for I50L/A71V.
