Fig 2.

Diversity of ECDs/CBDs found at the N and C termini of the four major endolysin classes centrally located (from all 723 putative endolysins): N-acetylmuramidases (blue scale), N-acetylglucosaminidases (purple), N-acetylmuramoyl-l-alanine, and carboxy/endopeptidases (green scale). CHAP (orange) can act as an amidase or peptidase. These four major classes have been centrally located to show all ECDs (with colors mentioned above) and CBDs (gray scale) found attached to their N and C termini. For the correct interpretation of the schematic representation, for all endolysins found with a CHAP domain, a GLUCO at their N terminus was observed. In some proteins, a GLUCO, AMI-2, and AMI-3 domain at the C terminus was identified.