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. 2013 Feb 28;288(15):10684–10691. doi: 10.1074/jbc.M112.420042

FIGURE 6.

FIGURE 6.

Proinflammatory effects of 6-OAU in vivo. A, 6-OAU (10 mg/kg) suspended in 1% rat serum or 1% rat serum as control was injected into the jugular vein in rats. Blood was collected from the jugular vein 3 h after 6-OAU injection. CXCL1 concentration in the serum was measured with a commercial ELISA kit. The data were expressed as the means ± S.D.; n = 5. **, p < 0.01 when compared with the 1% rat serum-injection group. B, 6-OAU suspended in 0.3% BSA or 0.3% BSA alone as control was injected into the dorsal air pouch prepared on rats. Infiltrated cells into the air pouch were collected with PBS 4 h after 6-OAU inoculation. The cell number was counted with the XT-2000i. The data were expressed as the means ± S.D.; n = 6. **, p < 0.01 and *, p < 0.05 when compared with the 0.3% BSA injection group.