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Binding of θ-defensin analogues to model membrane systems. a, P/L for the binding of θ-defensin analogues to a model membrane comprising an extract of phospholipids from E. coli. b, P/L ratio (mol/mol) for the binding of [Aba5,14]BTD-2 to four membrane systems. The 50:50 POPC/POPG mixture and extract of E. coli lipids are anionic and model bacterial membranes. POPC and the 50:50 POPC/POPE mixture are neutral and model mammalian membranes.
