Fig 1.

Dimerization domain and secondary structure comparison. (A) DsbA2 amino acid sequence depicting the leader sequence and the detached dimerization domain sequence deleted to create DsbA2N. The underlined sequences (27 amino acids) of the dimerization domain are conserved, and larger letters represent amino acids that are highly conserved among DsbA2 members listed in Table 2. The CXXC and cis-proline regions are in boldface. (B) Secondary structure predictions for L. pneumophila DsbA1, which is similar to DsbA of E. coli, E. coli DsbC, and L. pneumophila DsbA2 are depicted. The CXXC region and the cis-proline motifs are boxed. Note that the cis-P region of DsbA2 is similar to that of DsbC.