Table 4.
MICs of cationic antimicrobial peptides to Y. pestis KIM6+ strains
| Y. pestis strain or genotype | MIC (μg/ml) of: |
|
|---|---|---|
| Polymyxin B | Cecropin A | |
| KIM6+ (wild type) | 50 | >100 |
| ΔphoP (pLG338) | <0.1 | 1.6 |
| ΔphoP (pLGphoP) | 25 | >100 |
| ΔpmrA | 50 | >100 |
| ΔphoP ΔpmrA | 0.8 | 1.6 |
| ΔpbgP Δugd | <0.1 | 1.6 |
| Δugd (pLG338-30) | <0.1 | 1.6 |
| Δugd (pLGugd) | 50 | >100 |