Table 2.
Variable | No F3/F4 during first two years (N=368) | F3/F4 during first two year (N=101) | P-value |
---|---|---|---|
Recipient Race (% Black) | 19.0% | 34.7% | 0.002 |
Donor Race (% Black) | 19.3% | 12.9% | 0.1 |
Recipient/Donor Race Combination | 69.0% W/W (N=254) 12.0% W/B (N=44) 7.3% B/B (N=27) 11.7% B/W (N=43) |
59.4% W/W (N=60) 5.9% W/B (N=6) 6.9% B/B (N=7) 27.7% B/W (N=28) |
0.001 |
Recipient Gender (% Female) | 24.2% | 35.6% | 0.02 |
Donor Gender (% Female) | 62.5% | 66.3% | NS |
CMV High Risk (D+/R−) | 16.3% | 21.8% | 0.2 |
Combined Kidney transplant | 6.0% | 8.9% | NS |
Living Related transplant | 5.7% | 5.9% | NS |
Donation after cardiac death | 2.7% | 2.2% | NS |
HBV Surface Antigen Positive | 2.1% | 2.1% | NS |
Recipient Diabetes | 24.0% | 16.0% | 0.1 |
Hepatocellular Carcinoma | 21.0% | 17.2% | NS |
Alcohol Cirrhosis Comorbidity | 45.0% | 41.7% | NS |
Treated for acute rejection | 22.6% | 37.6% | 0.002 |
Treated for HCV recurrence | 32.3% | 38.6% | 0.2 |
Recipient Albumin | 2.9 ± 0.6 | 2.8 ± 0.7 | NS |
Recipient INR | 1.6 ± 0.9 | 1.7 ± 0.9 | NS |
Recipient Creatinine | 1.6 ± 1.5 | 1.6 ± 1.6 | NS |
Recipient Pre-transplant Log Viral Load | 5.5 ± 1.0 (N=133) | 5.8 ± 0.9 (N=43) | 0.1 |
Anti-Lymphocyte Induction | 37.5% | 39.2% | NS |
Recipient Age | 52.7 ± 7.4 | 50.7 ± 8.1 | 0.02 |
Donor Age | 38.3 ± 15.7 | 41.4 ± 14.8 | 0.07 |
Recipient BMI | 29.5 ± 14.1 | 29.7 ± 17.8 | NS |
Cold Ischemia Time (In Hours) | 6.8 ± 2.4 | 7.0 ± 5.0 | NS |
BMI: body mass index; HCV: Hepatitis C Virus; LT: Liver Transplantation; B/W: Black/White; D+/R−: Donor positive, recipient negative; NS: Non-significant; F3/F4: Fibrosis stage 3 or 4