Fig. 2.
The AR gene and encoded AR protein The AR gene consists of eight exons, encoding three domains in the AR protein: the transcription regulation domain (NTD), the DNA-binding domain (DBD) and the specific ligand-binding domain (LBD). Exon 1 contains the polymorphic CAG repeat, which encodes a polyglutamine (Gln) n tract in NTD. Elsevier granted permission to reproduce and modify this figure.