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Incorporation of prior interactions is data driven. For all three datasets, we used all GSIs as PKIs. Here, we display the distribution of time-lagged correlation of predicted TF-target pairs at a recall level of 
(higher ranked, blue), and low ranked interactions that are in the gold standard (lower ranked, red). Note that high ranked interactions are less likely to have low absolute time-lagged correlation, and the low ranked GSIs are centred around 0
