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. 2013 Jan 7;591(Pt 7):1707–1730. doi: 10.1113/jphysiol.2012.245787

Figure 4. PP-2A suppression recovered LTD under CaMKII suppression.

Figure 4

A and B, simulated time courses of amount of active PKC (A) and non-phosphorylated AMPARs (B) before and after the conditioning [Ca2+]i and glutamate increase in a model in which the amount of CaMKII is reduced to 10% without or with additional 50% reduction of PP-2A, PP-1, or calcineurin (CaN). C, relation between the amount of PP-2A, PP-1 or CaN and non-phosphorylated AMPAR fraction at 30 min after the conditioning stimulation.