Table 3.
Kinetics of enzymatic reactions
| ID | Km (μm) | kcat (s−1) | Previous version | Notes and references | ||
|---|---|---|---|---|---|---|
| e1, e2 | 3 | 2 | Same | See Kitagawa et al. (2009). | ||
| e3, e4 | 5 | 0.2 | 10 | 0.2 | PP-2A mediated dephosphorylation of CaMKII was assumed to be slightly stronger compared with Kawaguchi et al. (2011). | |
| e5 | — | 11 | 11 | See Kawaguchi et al. 2011. | ||
| e6 | — | 0.5 | 0.5 | See Kawaguchi et al. 2011. | ||
| e7 | 11 | 1 | Same | See Kitagawa et al. (2009). | ||
| e8 | 3 | 2 | Same | See Kitagawa et al. (2009). | ||
| e9 | 2.4 | 2.7 | Same | See Kitagawa et al. (2009). | ||
| e10 | 1.6 | 0.5 | Same | See Kawaguchi et al. (2011). | ||
| e11 | 5 | 2 | 2 | 0.4 | Dephosphorylation of DARPP-32, AMPARs, G-substrate, Raf and MAPKK were assumed to have similar kinetics. | |
| e12 | 12 | 5 | Same | See Kawaguchi et al. (2011). | ||
| e13 | 12 | 0.1 | Same | See Kitagawa et al. (2009). | ||
| e14 | 2 | 0.05 | Same | See Kitagawa et al. (2009). | ||
| e15 | 11 | 2 | Same | See Kawaguchi et al. (2011). | ||
| e16 | 2 | 0.5 | Same | See Kawaguchi et al. (2011). | ||
| e17 | 3.5 | 0.05 | Same | Tanaka et al. (2007). | ||
| e18 | 5 | 2 | 15.7 | 6 | Dephosphorylation of DARPP-32, AMPARs, G-substrate, Raf and MAPKK were assumed to have similar kinetics. | |
| e19 | 20 | 11.04 | Same | Kuroda et al. (2001); Tanaka et al. (2007). | ||
| e20 | 20 | 120 | Same | Kuroda et al. (2001); Tanaka et al. (2007). | ||
| e21 | 20 | 54 | Same | Kuroda et al. (2001); Tanaka et al. (2007). | ||
| e22 | 20 | 120 | Same | Kuroda et al. (2001); Tanaka et al. (2007). | ||
| e23 | 20 | 36 | Same | Kuroda et al. (2001); Tanaka et al. (2007). | ||
| e24 | 20 | 60 | Same | Kuroda et al. (2001); Tanaka et al. (2007). | ||
| e25 | 25.6 | 20 | Same | Tanaka et al. (2007) | ||
| e26 | 11.5 | 0.0335 | Same | Kuroda et al. (2001); Tanaka et al. (2007). | ||
| e27 | 5 | 2 | 15.7 | 6 | Dephosphorylation of DARPP-32, AMPARs, G-substrate, Raf and MAPKK were assumed to have similar kinetics. | |
| e28 | 0.398 | 0.105 | Same | Tanaka et al. (2007). | ||
| e29 | 5 | 2 | 15.7 | 6 | Dephosphorylation of DARPP-32, AMPARs, G-substrate, Raf and MAPKK were assumed to have similar kinetics. | |
| e30 | 0.0463 | 0.15 | Same | Tanaka et al. (2007). | ||
| e31 | 0.16667 | 1 | Same | Tanaka et al. (2007). | ||
| e32 | 2 | 15 | Newly defined | Francis et al. (2010). | ||
| e33 | 2 | 0.1 | Assumption | Francis et al. (2010). | ||
| e34 | 2 | 3 | 2 | 3.87 | Poppe et al. (2008); Francis et al. (2010). | |
| e35 | 0.2 | 2 | 0.2 | 0.72 | Hall et al. (1999). | |
| e36 | 5 | 2 | Newly defined | Hall et al. (1999). | ||
| e37 | 1.6 | 0.5 | Newly defined | CaN-mediated dephosphorylation of phospho-G substrate was assumed to take place with identical kinetics to that of phospho-DARPP-32, which are similar to the reports by King et al. (1984). | ||
| e38 | 5 | 48 | Same | Kuroda et al. (2001). | ||