Table 2.
Two-way ANOVA results for CT and GL nerve responses to taste compounds (T1R1−/− vs. T1R1+/− mice)
| CT nerve | GL nerve | |||
|---|---|---|---|---|
| Tastant | Degrees of freedom | F value | Degrees of freedom | F value |
| MSG | 1,84 | 35.5*** | 1,95 | 0.2 |
| Interaction | 4,84 | 6.9*** | 4,95 | 0.1 |
| MSG + IMP | 1,81 | 134.5*** | 1,95 | 0.0 |
| Interaction | 4,81 | 0.0 | 4,95 | 0.2 |
| MPG | 1,100 | 15.2*** | 1,72 | 0.0 |
| Interaction | 4,100 | 7.0*** | 4,72 | 0.4 |
| MPG + IMP | 1,81 | 61.6*** | 1,59 | 1.1 |
| Interaction | 4,81 | 0.2 | 4,59 | 0.2 |
| IMP | 1,56 | 6.6* | 1,48 | 0.0 |
| Interaction | 4,56 | 1.8 | 4,48 | 0.0 |
| NaCl | 1,71 | 0.3 | 1,66 | 0.2 |
| Interaction | 4,71 | 0.1 | 4,66 | 0.1 |
| KCl | 1,71 | 0.1 | 1,47 | 0.0 |
| Interaction | 4,71 | 0.2 | 4,47 | 0.0 |
| HCl | 1,82 | 0.2 | 1,79 | 0.2 |
| Interaction | 4,82 | 0.0 | 4,79 | 0.2 |
| Sucrose | 1,80 | 23.8*** | 1,93 | 0.1 |
| Interaction | 5,80 | 2.9* | 5,93 | 0.0 |
| SC45647 | 1,59 | 8.8** | 1,54 | 0.0 |
| Interaction | 3,59 | 0.2 | 3,54 | 0.0 |
| Acesulfame K | 1,50 | 7.2* | 1,98 | 0.0 |
| Interaction | 4,50 | 0.6 | 4,98 | 0.1 |
| QHCl | 1,97 | 0.6 | 1,85 | 0.0 |
| Interaction | 6,97 | 0.1 | 6,85 | 0.1 |
| QSO4 | 1,66 | 0.4 | 1,55 | 0.0 |
| Interaction | 3,66 | 0.1 | 3,55 | 0.0 |
| Denatonium | 1,63 | 0.5 | 1,48 | 0.0 |
| Interaction | 3,63 | 0.4 | 3,48 | 0.1 |
The effects of genotype were analysed by two-way ANOVA. The table is based on data shown in Figs 1–4. Top numbers for each chemical relate to the main effect (genotype) and bottom numbers to the interaction effect (genotype × concentration). *P < 0.05, **P < 0.01, ***P < 0.001, ANOVA. Abbreviations: CT, chorda tympani; GL, glossopharyngeal; IMP, inosine monophosphate; MPG, monopotassium glutamate; MSG, monosodium glutamate; QHCl, quinine hydrocholoride; and QSO4, quinine sulfate.