Table 3.
Two-way ANOVA results for CT and GL nerve responses to 300 mm MSG with various concentrations of mGluR antagonists (T1R1−/− vs. T1R1+/− mice)
CT nerve | GL nerve | |||
---|---|---|---|---|
Antagonist | Degrees of freedom | F value | Degrees of freedom | F value |
AIDA | 1,47 | 1.1 | 1,56 | 17.2*** |
Interaction | 4,47 | 0.4 | 4,56 | 1.5 |
CPPG | 1,45 | 2.3 | 1,50 | 6.7* |
Interaction | 4,45 | 0.4 | 4,50 | 0.4 |
AIDA + CPPG | 1,57 | 1.8 | 1,57 | 6.6* |
Interaction | 4,57 | 0.1 | 4,57 | 0.7 |
The effects of genotype were analysed by two-way ANOVA. The table is based on data shown in Fig. 8. Top numbers for each chemical relate to the main effect (genotype) and bottom numbers to the interaction effect (genotype × concentration). *P < 0.05, ***P < 0.001, ANOVA. Abbreviations: AIDA, (RS)-1-aminoindan-1,5-dicarboxylic acid; CPPG, (RS)-α-cyclopropyl-4- phosphonophenylglycine; CT, chorda tympani; GL, glossopharyngeal; mGluR, metabotropic glutamate receptor; and MSG, monosodium glutamate.