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. Author manuscript; available in PMC: 2013 Apr 12.
Published in final edited form as: Genet Epidemiol. 2010 Dec 31;35(2):111–118. doi: 10.1002/gepi.20556

TABLE I.

Empirical power for detecting simulated “causal” SNPs and theoretical power predicted by Quanto. Type I error threshold 8.2×10−8 (Bonferroni corrected) was used.

Sample Size Effect Size (R2)
0.25% 0.5% 1% 2% 4%
1,000 0.00/0.00 0.00/0.00 0.01/0.01 0.15/0.19 0.88/0.85
2,000 0.00/0.00 0.02/0.01 0.19/0.19 0.78/0.84 1.00/1.00
4,000 0.02/0.03 0.20/0.19 0.86/0.84 1.00/1.00 1.00/1.00
8,000 0.19/0.19 0.86/0.83 1.00/1.00 1.00/1.00 1.00/1.00

The first number represents empirical power from simulation study; and the second stands for theoretical power from Quanto. Empirical power results were averaged over SNPs with the same R2 value.