Table 1.
Characteristic | FES group (N = 24) | HC group (N = 22) |
---|---|---|
Agea (mean ± SD) | 27.3 ± 4.8 | 27.5 ± 3.3 |
Mean time from psychotic episode (months, mean ± SD) | 8 ± 5 | n.a. |
Handedness scorea (mean ± SD) | 65.3 ± 18.1 | 69.3 ± 15.8 |
Male/femalea | 16/8 | 12/10 |
Diagnosis | (First episode) Schizophrenia | n.a. |
Intelligence Quotient (mean ± SD) | 100 ± 8.5 | n.a. |
EQb mean ± SD (cognitive empathyc/emotional reactivityc/social skillsd) | 38 ± 11.4 (12.4 ± 5.4/2.2 ± 5.2/6.3 ± 2.8) | 45.4 ± 9.7 (14.5 ± 4.6/14.6 ± 4.4/8.1 ± 2.3) |
SCID-II Cluster A | n.a. | Negative |
SCID-II Cluster B | n.a. | Negative |
SCID-II Cluster C | n.a. | Negative |
PANSS positive scale individual scores (mean ± SD) | 16 10 9 14 17 16 21 14 12 16 18 12 10 12 13 11 19 13 8 13 9 10 11 15 (13.3 ± 3.4) | n.a. |
PANSS negative scale individual scores (mean ± SD) | 8 10 10 9 10 11 12 16 12 24 12 8 10 9 11 9 11 22 9 14 9 8 12 22 (12 ± 4.5) | n.a. |
PANSS general psychopathology scale individual scores (mean ± SD) | 22 20 20 30 18 24 32 25 22 37 22 22 20 20 23 21 25 25 19 25 20 19 22 35 (23.6 ± 5) | n.a. |
SPI-A total individual scores (mean ± SD) | 138 28 74 91 115 71 67 5 0 114 40 36 97 17 12 27 42 22 83 82 45 40 49 85 (61.1 ± 38.4) | n.a. |
Medicatione | 6 Quetiapine, 7 Risperidone, 3 Paliperidone, 4 Aripiprazole, 3 Olanzapine 1 Drug Free | n.a. |
aNo significant differences between the HC and FEP groups.
bSignificant difference between the HC and FEP group (P = 0.02).
cNo significant differences between the HC and FEP group.
dSignificant difference between the HC and FEP group (P = 0.02).
eClorpromazine equivalent mean dose = 422 mg/die SD = 395.5 (calculated on 21 patients because no equivalents are available for paliperidone).
SCID-II, Structured Clinical Interview for DSM-IV Axis II personality Disorders; n.a., not applicable.