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. Author manuscript; available in PMC: 2013 Apr 12.
Published in final edited form as: Am J Transplant. 2011 Aug 30;11(11):2499–2507. doi: 10.1111/j.1600-6143.2011.03700.x

Figure 5. STN depresses T cell activation in rat in vitro T cell cultures.

Figure 5

(A) Western blot-assisted phospho-PKCθ and phospho-IκBα expression in ConA-stimulated T cells. Representative of n=3.

(B) Quantitative RT-PCR-assisted detection of IL-2 in Con A-stimulated T cells. *p<0.005, **p<0.001, n=3/group.

(C) IFN-γ production in Con A-stimulated T cells. *p<0.005, n=3/group.

(D–E) TNF-α and IL-1β production in Con A-stimulated T cell - macrophages co-cultures. STN suppressed TNF-α/IL-1β levels. *p<0.05, **p<0.005, n=3/group. No effect of STN on TNF-α/IL-1β in macrophage cultures devoid of T cells.