Figure 7. Aβ on force of membrane tether formation (F_mtf) mediated by sLe^x-selectin bonding.

(A) F_mtf was measured at the sudden drop of force when a rupture of a membrane tether occurred (Fig. 2A). A bar graph summarizes F_mtf measured for cells treated with histamine, Aβ, lovastatin and latrunculin A. ***p≤0.001, **p≤0.01, *p≤0.05 compare to the control; °°p≤0.01 compare to the Aβ (1 µM) treatment group. (B) The distributions of F_mtf were plotted for different experimental groups. F_mtf distribution for the control group is represented in unfilled bars, and superimposed with other experimental groups represented in grey bars for comparison.