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. 2013 Mar 26;110(15):6121–6126. doi: 10.1073/pnas.1215870110

Table 5.

Univariate Cox regression analysis of post-RP BCF using 32-gene risk index scores from needle biopsy tissue samples

Variable HR (95% CI) P value
32-Gene risk index 4.92 (1.45–16.78) 0.0107
Gleason score at biopsy 0.0162
 7 vs. ≤6 3.21 (2.96–3.48) 0.0052
 ≥8 vs. ≤6 2.80 (0.78–10.06) 0.1155
cT stage (2 vs. 1) 0.83 (0.25–2.76) 0.7638
Proportion of cores positive (>⅓ vs. ≤⅓) 1.03 (0.48–2.23) 0.9306
Highest percent positive core 1.00 (0.88–1.13) 0.9955
Log(1+baseline PSA) 2.09 (1.19–3.65) 0.0098

Validation cohort, n = 79.

The HR calculated for the 32-gene index is based on a five-unit change. All variables are pre-RP values.