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. 2013 Mar 26;110(15):6121–6126. doi: 10.1073/pnas.1215870110

Table 6.

Multivariate Cox regression analysis of post-RP BCF using 32-gene risk index scores from needle biopsy tissue samples

Variable HR (95% CI) P value
32-Gene risk index 7.57 (1.15–49.49) 0.0345
Gleason score at biopsy 0.0474
 7 vs. ≤6 2.30 (0.83–6.36) 0.1090
 ≥8 vs. ≤6 0.46 (0.07–3.21) 0.4345
cT stage (2 vs. 1) 1.60 (0.41–6.30) 0.5011
Proportion of cores positive (>⅓ vs. ≤⅓) 1.08 (0.43–2.73) 0.8669
Highest percent positive core 0.90 (0.76–1.06) 0.2109
Log(1+baseline PSA) 2.15 (1.10–4.20) 0.0253

Validation cohort, n = 79.

The HR calculated for the 32-gene index is based on a five-unit change. All variables are pre-RP values.