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. 2013 Mar 25;110(15):5806–5811. doi: 10.1073/pnas.1216719110

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Fig. 3. — Cross-resistance between Cry1A and Cry2A in 21 selection experiments. Insect strains were selected for resistance to a Cry1A toxin and subsequently evaluated for cross-resistance to Cry2A, or vice versa. The CRR is the LC₅₀ (or IC₅₀) of the toxin not used for selection (e.g., Cry2Ab) for the strain selected with the other toxin (e.g., Cry1Ac) divided by the LC₅₀ (or IC₅₀) of the toxin not used for selection (e.g., Cry2Ab) for an unselected, control strain. The expected value of log (CRR) is 0 if cross-resistance is absent and >0 if cross-resistance occurs. Nineteen of the 21 ratios were >0, indicating significant cross-resistance between Cry1A and Cry2A toxins. Insect strains were from the following species: Diatracea saccharalis (Ds), H. armigera (Ha), Helicoverpa punctigera (Hp), Heliothis virescens (Hv), H. zea (Hz), Pectinophora gossypiella (Pg), Plutella xylostella (Pg), and Trichoplusia ni (Tn).