Simulated effects of refuge percentage, dominance, and redundant killing on evolution of resistance to two-toxin Bt cotton. The RKF was either 1, which represents the ideal condition of complete redundant killing, or 0.64, which reflects the higher survival on two-toxin Bt cotton for individuals selected for resistance to one toxin (Cry1Ac) relative to susceptible individuals, based on empirical data for survival of the GA-R strain relative to the GA strain (Fig. 2). Table S3 gives fitness values for each genotype under each set of conditions simulated.