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Subcellular localization of CCDC41. (A) Schematic representation of CCDC41 and its domain structure. (B) Double-immunofluorescent localization of CCDC41 in RPE1 cells. (C) RPE1 cells were double-labeled with the indicated antibody pairs. Ciliogenesis was induced by 24 h serum starvation (Right). (D) U2OS cells were transfected with CP110 siRNAs for 3 d to induce abnormal centriole elongation and double-labeled with the indicated antibody pairs. (Scale bars: B, 5 μm; C and D, 1 μm.)
