Fig. 4.

C5a inhibition preserves microvascular flow in C3^−/− recipients. (A) FITC-lectin perfusion profile of whole mounts tracheal grafts from d8 to d12 in C3^−/− recipients and NOX-D19–treated recipients shows early recovery in microvascular flow during allograft rejection. Original magnification, 20×. (B) Morphometric assessments of perfused vasculature (FITC-lectin perfused vessels per unit area) in tracheal grafts at different time points (n = 4–6 animals per time point per group). Data are shown as means with SEM. *P < 0.05.