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. Author manuscript; available in PMC: 2014 Feb 27.
Published in final edited form as: J Am Chem Soc. 2013 Feb 8;135(8):3173–3185. doi: 10.1021/ja311408y

Table 1.

WT insulin
(biosynthetic)
DKP insulin
(biosynthetic)
L-DKP
ester
insulin
D-DKP
ester insulin
L-DKP
insulin
D-DKP
insulin
Kd
(nM)
0.060 ± 0.009 0.029 ± 0.005 30.0 ± 0.3 > ~2000 0.016 ±
0.003
>~1200