Serial PET imaging of CD105 expression in 4T1 tumor-bearing BALB/c mice. a Serial coronal PET images at 0.5, 2, 5, 16, and 24 h post-injection of 64Cu-NOTA-TRC105-Fab, or 64Cu-NOTA-TRC105-Fab after a pre-injected 2 mg blocking dose of TRC105. b Representative PET/CT images of 4T1 tumor-bearing mice at 5 h post-injection of 64Cu-NOTA-TRC105-Fab. c Serial coronal PET images at 0.5, 3, and 8 h post-injection of 61Cu-NOTA-TRC105-Fab in 4T1 tumor-bearing mice. Arrowheads indicate the 4T1 tumors.