Table 6.
CRP at or above versus below the 95th percentile and diabetic retinopathy endpoints in the DCCT
| Endpoint | Relative Risk (95% CI) | |||
|---|---|---|---|---|
| Tx | Tx + HbA1c | Full Model* | Number of incident Cases/Total N at or above 95th percentile | |
| Progression | 1.59 (0.98–2.57) | 1.20 (0.74–1.94) | 1.22 (0.75 – 2.00) | 18/68 |
| CSME | 1.67 (0.87–3.20) | 1.23 (0.63–2.38) | 1.81 (0.90 – 3.63) | 10/68 |
| Hard Exudate | 2.79 (1.64–4.74) | 2.09 (1.21–3.61) | 2.38 (1.35 – 4.19) | 16/68 |
| PDR | 3.67 (1.90–7.06) | 2.79 (1.43–5.41) | 2.91 (1.39 – 6.08) | 11/68 |
*
Additionally adjusted for age, sex, duration of diabetes, body mass index, smoking status (never, past, current), and total/HDL cholesterol ratio.
All models [Tx, Tx+HbA1c, and Full Model] are also adjusted for baseline retinopathy stratum.