Table 1.

Dose Reduction Opportunities in Myocardial Perfusion Imaging

Radiopharmaceutical Selection

Tc-99m-based tracers lower patient dose compared to Tl-201

PET tracers (N-13 ammonia, Rb-82) lower patient dose compared to SPECT tracers

Protocol Selection, e.g. Stress-First/Stress-Only Imaging

Administered Activities Chosen

Weight-based administered activity

Post-Administration

Hydration and early micturition can reduce dose to genitourinary system

Technological Advancements

Software

Iterative reconstruction

Resolution recovery

Noise reduction

Hardware

Solid-state camera