Fig. 8. Down-regulation of HNF-4α target genes by miR-34a, miR-34c-5p and miR-449a.
The mRNA expression levels of HNF-4α target genes, TTR, ApoB and α1-AT in HepG2 cells, transfected with indicated miRNA mimics as described in Fig. 4 legend, were examined by RTqPCR. Each column represents the mean ± SD of three independent experiments. The data are relative to that transfected with siControl (miR-Ctr), ** p<0.01.