Table 2.
Post-solid organ transplant t-MNs at the University of Chicago.
| Patient 1 | Patient 2 | Patient 3 | Patient 4 | Patient 5 | |
|---|---|---|---|---|---|
| Age/sex (years) | 57/M | 56/M | 50/M | 58/F | 55/F |
| Organ transplant | Heart | Kidney | Heart | Liver | Kidney |
| Immuno-suppressive therapy | CsA MMF Prednisone |
CsA MMF Prednisone |
CsA azathioprine Prednisone |
CsA azathioprine Prednisone |
Cytoxan Prednisone |
| Latency (years) | 4.3 | 4.4 | 12.3 | 7.7 | 7 |
| WHO classification | t-AML | t-AML | t-MDS | t-MDS | t-MDS |
| Treatment | Induction chemo + allo-HCT | Induction chemo + allo-HCT | Induction chemo + auto-HCT | Induction chemo | Supportive care |
| Survival (years) | 1 | 1.5 | 3.6 | 1.3 | 1.9 |
| Karyotype | 46XY, inv(9)c, t(10;11) | Normal | 46XY, 55%; 46XY, del 7, 25%; 46XY, del 11, 20% | Normal | 46XX, 55%; 46XX, inv(9)c, del 7, 41%; 46XX, inv(9)c, del 19, 4% |