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Regulation of migration, collagen synthesis, and MCP-1 expression in HPASMCs by GW501516. PDGF-stimulated (a) cell migration, (b) collagen synthesis, and (c) TNF-induced MCP-1 mRNA expression were significantly inhibited by GW501516. Experiments were performed in triplicate and repeated a minimum of three times. # P < 0.01, † P < 0.05 versus control; *P < 0.05 versus PDGF/TNF-treated cells.
