Table 1.
Effect of ASEAF on the insulin resistant state of the diabetic rats. The insulin sensitivity indexes (HOMA and QUICKI) were used to quantify the effect. The index values before and after 250 mg/kg ASEAF oral administration were shown.
| HOMA index | QUICKI | |||
|---|---|---|---|---|
| Before | After | Before | After | |
| Negative | 1.563 ± 0.169 | 1.197 ± 0.038 | 0.280 ± 0.003 | 0.289 ± 0.001 |
| Pioglitazone | 1.746 ± 0.348 | 0.646 ± 0.103a,b | 0.279 ± 0.005 | 0.316 ± 0.006a,d |
| ASEAF | 1.616 ± 0.302 | 0.689 ± 0.109a,c | 0.282 ± 0.006 | 0.313 ± 0.005a,b |
Data shown are the calculated index values and are presented as mean ± SEM, 6 rats (n = 6) per group; a P < 0.001 versus negative control group; b P < 0.01; c P < 0.05; d P < 0.001 versus before treatment.