Table 5.
Microbiologic etiology by IE type in 2781 patients with definite endocarditis.
| Native Valve IE |
Intracardiac-Device IE |
|||
|---|---|---|---|---|
| Drug Abusers (n=237) n (%) | Non-Drug Abusers (n=1644) n (%) | PVIE (n=563) n (%) | Other devices (n=172)a n (%) | |
| S. aureus | 160 (68) | 457 (28) | 129 (23) | 60 (35) |
| Coag Neg staph. | 7 (3) | 148 (9) | 95 (17) | 45 (26) |
| Viridans group strep | 24 (10) | 345 (21) | 70 (12) | 14 (8) |
| S. bovis | 3 (1) | 119 (7) | 29 (5) | 5 (3) |
| Other strep | 5 (2) | 118 (7) | 26 (5) | 7 (4) |
| Enterococci | 11 (5) | 179 (11) | 70 (12) | 10 (6) |
| HACEK | 0 (0) | 30 (2) | 13 (2) | 1 (1) |
| Fungi / Yeast | 3 (1) | 16 (1) | 23 (4) | 2 (1) |
| Polymicrobial | 6 (3) | 16 (1) | 5 (1) | 0 (0) |
| Culture negative | 12 (5) | 154 (9) | 65 (12) | 18 (11) |
| Other | 6 (3) | 62 (4) | 38 (7) | 10 (6) |
| Surgical therapy | 89/234 (38)b | 784/1639 (48) | 274/561 (49) | 104/172 (61) |
| In-hospital mortality | 23/236 (10)b | 281/1643 (17) | 131/561 (23) | 17/172 (10) |
Abbreviations : IE = infective endocarditis; strep = streptococci; HACEK = Haemophilus spp., Aggregatibacter (formerly Actinobacillus) actinomycetemcomitans, Cardiobacterium hominis, Eikenella corrodens, and Kingella species; PVIE = prosthetic valve infective endocarditis.
a
Including pacemakers and implantable cardioverter defibrillators.
b
For pure right-sided IE only: 23/107 (22%) had surgical therapy and 6/108 (6%) died in hospital.