Table 3.
Median inflammatory mediator values for neonates who did (BPD+) and did not develop (BPD−). Data represent median (25th %, 75th %) and are measured in pg/mL after log transformation. P-values from the comparisons of individual biomarkers between the BPD groups are displayed.
| Inflammatory Mediator | Median (25th – 75th %) | P-value | |
|---|---|---|---|
| BPD− | BPD+ | ||
| IL-1ra | 8.42 (6.14, 9.53) | 8.87 (6.96, 9.68) | 0.730 |
| IL-1b | 6.23 (3.84, 8.25) | 5.92 (4.23, 8.51) | 0.961 |
| IL-4 | 4.11 (3.22, 5.77) | 3.71 (3.47, 4.44) | 0.324 |
| IL-6 | 8.62 (8.13, 10.09) | 8.95 (8.40, 9.84) | 0.921 |
| IL-8 | 10.16 (10.04, 10.24) | 10.18 (10.06, 10.21) | 0.921 |
| IL-10 | 5.20 (3.37, 6.96) | 4.38 (3.91, 6.15) | 0.961 |
| GMCSF | 5.96 (4.76, 6.96) | 5.56 (4.45, 6.15) | 0.199 |
| MCP-1b | 10.18 (10.07, 10.22) | 10.17 (10.12, 10.22) | 0.844 |
| MIP-1a | 4.63 (4.96, 10.17) | 8.62 (5.14, 9.86) | 0.521 |
| MIP-1b | 7.83 (4.57, 9.55) | 7.77 (5.30, 9.02) | 0.969 |
| TNF-alpha | 6.28 (4.04, 8.48) | 5.83 (4.35, 9.04) | 0.961 |
| VEGF | 6.43 (5.02, 7.95) | 6.59 (4.72, 6.84) | 0.675 |